- German Bernd Schuster takes over as coach after Fabio Capello.
- Roberto Carlos leaves on a free transfer to Turkish Fenerbahce.
- Fellow Brazilians Emerson (AC Milan) and Cicinho (Roma) move to Serie A.
- David Beckham moves to LA Galaxy.
- Portuguese defender Pepe moves from Porto.
- Argentine defender Gabriel Heinze moves from Manchester Utd.
- Dutch winger Arjen Robben moves from Chelsea.
- Argentine striker Javier Saviola moves from Barcelona.
- Dutch midfielder Wesley Sneijder comes from Ajax.
- Dutch full back Van Bronckhorst leaves for Feyenoord.
- Argentine striker Saviola moves to Real.
- French winger Giuly moves to Roma.
- French striker Thierry Henry arrives from Arsenal.
- French defender Eric Abidal comes from Lyon.
- Argentine striker Gabriel Milito comes from Zaragoza
- Fernando Torres leaves Atletico Madrid for Liverpool
- Luis Garcia (Liverpool), Forlan (Villarreal) and Reyes (Arsenal) arrive at Atletico Madrid.
- Hector Cuper former Valencia and Inter coach takes over at Betis.
- Danish Michael Laudrup takes over as coach of Getafe after that Schuster leaves for Real.
- Argentine defender Roberto Ayala leaves Valencia for Zaragoza.
- The season open with the Madrid derby between Real and Atletico on Saturday 25 August.
- On Sunday Barcelona start at Racing Santander and Villarreal travel to Valencia.